Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 1059
interventional 931
Observational 120
Registry 8

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 343
Biological 108
Drug|Other 64
Biological|Drug 48
Drug|Procedure 44
Biological|Drug|Other 24
Biological|Drug|Procedure|Radiation 23
Drug|Radiation 23
Drug|Procedure|Radiation 22
Biological|Drug|Other|Procedure|Radiation 17
Procedure 17
Behavioral 16
Drug|Other|Procedure|Radiation 16
Other 16
Biological|Other 14
Biological|Drug|Radiation 12
Device 9
Biological|Drug|Other|Procedure 8
Biological|Drug|Procedure 8
Drug|placebo 8
Device|Drug|Procedure 6
Drug|Other|Procedure 6
Dietary Supplement 5
Drug|Genetic 5
Drug|Genetic|Other 5
Drug|Other|Radiation 5
Biological|Device|Drug 4
Genetic 4
Biological|Other|Procedure 3
Combination Product 3
Other|Procedure 3
Behavioral|Other 2
Biological|Drug|Other|Radiation 2
Biological|Other|placebo 2
Device|Drug 2
Device|Other 2
Diagnostic Test|Drug|Genetic|Procedure|Radiation 2
Dietary Supplement|placebo 2
Behavioral|Dietary Supplement|Other 1
Behavioral|Drug|Other|Procedure 1
Biological|Device 1
Biological|Device|Drug|Other 1
Biological|Device|Drug|Other|Procedure 1
Biological|Device|Drug|Procedure|Radiation 1
Biological|Device|Drug|Radiation 1
Biological|Drug|Genetic|Other 1
Biological|Drug|placebo 1
Biological|Genetic|Other|Procedure 1
Biological|placebo 1
Biological|Procedure 1
Biological|Procedure|Radiation 1
Combination Product|Drug 1
Device|Drug|Other 1
Device|Drug|Other|Procedure|Radiation 1
Device|Drug|Procedure|Radiation 1
Diagnostic Test 1
Diagnostic Test|Drug 1
Dietary Supplement|Drug 1
Dietary Supplement|Other 1
Drug|Genetic|Other|Procedure|Radiation 1
Drug|Genetic|Procedure|Radiation 1
Drug|Other|placebo|Procedure 1
Drug|placebo|Procedure 1
Genetic|Other 1
Genetic|Procedure 1
Procedure|Radiation 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 534
China 70
Germany 23
United States|Canada 21
France 20
Italy 19
Spain 17
NA 14
Japan 13
United States|Australia|Canada 11
United Kingdom 9
Korea, Republic of 7
United States|Germany|Italy 6
Canada 5
Russian Federation 5
United States|Italy 5
Denmark 4
Mexico 4
United States|Australia|Canada|Puerto Rico 4
United States|Canada|Puerto Rico 4
Denmark|Finland|Iceland|Norway|Sweden 3
Turkey 3
United States|Australia|Canada|Netherlands|Puerto Rico|Switzerland 3
United States|Australia|Canada|New Zealand|Puerto Rico 3
United States|Australia|Canada|New Zealand|Switzerland 3
Egypt 2
Germany|Switzerland 2
Iran, Islamic Republic of 2
Israel 2
Switzerland 2
United States|Australia 2
United States|Australia|Canada|Ireland|New Zealand|Puerto Rico|Switzerland 2
United States|Australia|Canada|New Zealand 2
United States|Denmark|Germany 2
United States|France|Germany|Italy|United Kingdom 2
United States|Germany 2
Argentina|Australia|Austria|Belarus|Belgium|Canada|Chile|Croatia|Czechia|Denmark|Finland|France|Germany|Greece|Hungary|Israel|Italy|Malaysia|Mexico|Netherlands|New Zealand|Norway|Poland|Romania|Saudi Arabia|Slovakia|Slovenia|Spain|Sweden|Switzerland|Turkey 1
Argentina|Austria|Belgium|Chile|Czech Republic|Germany|Hungary|Italy 1
Argentina|Belgium|Canada|Denmark|Finland|France|Italy|Netherlands|Norway|Sweden 1
Armenia|Belarus|Kyrgyzstan|Russian Federation|Uzbekistan 1
Australia|Austria|Belgium|Czechia|Denmark|Finland|France|Germany|Ireland|Israel|Italy|Japan|Netherlands|Norway|Poland|Portugal|Sweden|Switzerland|United Kingdom 1
Australia|Austria|Belgium|Czechia|Denmark|Finland|France|Israel|Italy|Netherlands|Norway|Poland|Portugal|Sweden|United Kingdom 1
Australia|Austria|Czechia|Germany|Israel|Italy|Slovakia|Switzerland 1
Australia|Austria|Czechia|Germany|Israel|Italy|Switzerland 1
Australia|Belgium|France|Germany|Italy|Korea, Republic of|Netherlands|Singapore|Spain|Sweden|United Kingdom 1
Australia|United Kingdom 1
Austria|Belgium|Canada|France|Germany|Italy|Japan|Norway|Spain 1
Austria|Belgium|China|Czechia|Denmark|Finland|France|Germany|Hungary|Ireland|Israel|Italy|Netherlands|Norway|Poland|Portugal|Russian Federation|Slovakia|Spain|Sweden|Switzerland 1
Austria|Belgium|France|Germany|Italy|Netherlands|Poland|Romania|Russian Federation|Spain|United Kingdom 1
Austria|Czechia|Germany|Italy|Poland|United Kingdom 1
Austria|Finland|Germany|Russian Federation 1
Austria|France|Germany|Italy|Netherlands|United Kingdom 1
Austria|Germany|Switzerland 1
Bangladesh 1
Belarus 1
Belarus|Russian Federation|Uzbekistan 1
Belgium 1
Belgium|Brazil|United States|Australia|Canada|Czechia|Hungary|Korea, Republic of|Mexico|New Zealand|Poland|Puerto Rico|Russian Federation 1
Belgium|Canada|Croatia|Germany|Portugal|United Kingdom 1
Belgium|Canada|Germany|United Kingdom 1
Belgium|Croatia|Czech Republic|France|Germany|Italy|Netherlands|Portugal|Slovakia|Turkey 1
Belgium|Denmark|Estonia|Finland|Germany|Iceland|Ireland|Lithuania|Netherlands|Norway|Portugal|Sweden|United Kingdom 1
Belgium|Denmark|France|Germany|Italy|Netherlands|Spain|Sweden|United Kingdom 1
Belgium|France 1
Belgium|France|Germany|Italy 1
Belgium|Netherlands 1
Brazil 1
Canada|United States|Australia|New Zealand|Switzerland 1
Denmark|Estonia|Finland|Lithuania|Norway|Sweden 1
Denmark|Sweden 1
France|Argentina|Australia|Austria|Belgium|Brazil|Czechia|Denmark|Germany|Greece|Israel|Italy|Mexico|Netherlands|Norway|Poland|Portugal|Romania|Russian Federation|Spain|Sweden|Switzerland|Turkey|United Kingdom 1
France|Germany|Italy|United Kingdom 1
France|Germany|Spain 1
Germany|Netherlands 1
Germany|Netherlands|United Kingdom 1
Germany|United States|Australia|Austria|Belgium|Canada|Denmark|Finland|France|Hong Kong|Italy|Korea, Republic of|Netherlands|New Zealand|Norway|Poland|Singapore|Spain|Sweden|Switzerland|Taiwan|United Kingdom 1
Hong Kong 1
Hong Kong|Japan|Malaysia|Singapore|Taiwan 1
Italy|Saudi Arabia|United Kingdom 1
Italy|United Kingdom 1
Kenya|Zimbabwe 1
Malaysia 1
Netherlands 1
Netherlands|United Kingdom 1
Singapore 1
South Africa 1
Sweden 1
United States|Argentina|Australia|Austria|Belarus|Brazil|Bulgaria|Canada|Finland|France|Greece|Italy|Korea, Republic of|Poland|Russian Federation|Spain|Taiwan|Turkey 1
United States|Argentina|Australia|Austria|Belgium|Brazil|Canada|Czech Republic|Denmark|Finland|France|Germany|Greece|Hungary|Ireland|Israel|Italy|Korea, Republic of|Netherlands|Norway|Peru|Philippines|Poland|Russian Federation|Singapore|South Africa|Spain|Sweden|Switzerland|Taiwan|Thailand|United Kingdom 1
United States|Argentina|Australia|Austria|Belgium|Brazil|Canada|Denmark|Finland|France|Germany|Israel|Italy|Korea, Republic of|Netherlands|Norway|Peru|Sweden|Switzerland|United Kingdom 1
United States|Argentina|Australia|Canada|China|Czechia|Finland|France|Germany|Hungary|Italy|Japan|Korea, Republic of|Netherlands|Poland|Singapore|Spain|Sweden|Taiwan|United Kingdom 1
United States|Australia|Austria|Belgium|Canada|France|Germany|Italy|Japan|Norway|Spain 1
United States|Australia|Austria|Canada|Denmark|France|Israel|Italy|Netherlands|Spain|Switzerland|United Kingdom 1
United States|Australia|Belgium|Hungary|India|Poland|Singapore|Spain|Taiwan|Turkey 1
United States|Australia|Brazil|Canada 1
United States|Australia|Canada|France|Germany|Netherlands|Switzerland|United Kingdom 1
United States|Australia|Canada|Italy|Puerto Rico|United Kingdom 1
United States|Australia|Canada|Netherlands|New Zealand|Puerto Rico|Switzerland 1
United States|Australia|Canada|New Zealand|Puerto Rico|Saudi Arabia 1
United States|Australia|Canada|Puerto Rico|Switzerland 1
United States|Australia|Canada|Switzerland 1
United States|Australia|France|Germany|Italy|Japan|Korea, Republic of|Netherlands|Singapore|Spain 1
United States|Australia|France|Poland 1
United States|Austria|Belgium|Czech Republic|France|Germany|Ireland|Italy|Netherlands|Sweden|United Kingdom 1
United States|Austria|Canada|France|Germany|Italy|Netherlands 1
United States|Belgium|Canada|Croatia|France|Germany|Israel|Italy|Netherlands|Portugal|Spain|Sweden|United Kingdom 1
United States|Belgium|Canada|Denmark|Finland|France|Germany|Italy|Netherlands|Norway|Spain|United Kingdom 1
United States|Belgium|France|Germany|Israel|Italy|Netherlands|Spain|Sweden|United Kingdom 1
United States|Belgium|France|Italy|Netherlands|Spain 1
United States|Brazil|France|Israel|Italy|Netherlands|Portugal|Singapore|Spain|United Kingdom 1
United States|Brazil|France|Italy|Korea, Republic of|Netherlands|Russian Federation|United Kingdom 1
United States|Canada|France|Germany|Netherlands 1
United States|Canada|France|Netherlands 1
United States|Canada|France|Netherlands|Spain|United Kingdom 1
United States|Canada|Germany|Israel|United Kingdom 1
United States|Canada|Israel|Puerto Rico 1
United States|Canada|Netherlands|Puerto Rico|Switzerland 1
United States|Canada|New Zealand 1
United States|Canada|Puerto Rico|Switzerland 1
United States|Denmark 1
United States|Egypt|India 1
United States|France 1
United States|France|Germany 1
United States|France|Germany|Israel|Italy 1
United States|France|Germany|Italy|Spain|United Kingdom 1
United States|France|Germany|Italy|Switzerland|United Kingdom 1
United States|France|Italy|Spain 1
United States|France|Japan|United Kingdom 1
United States|France|Spain|United Kingdom 1
United States|Germany|Israel 1
United States|Germany|Netherlands 1
United States|Italy|Netherlands|Singapore|Spain 1
United States|Puerto Rico 1
United States|Puerto Rico|South Africa 1
United States|United Kingdom 1

Sites per Study

Site_count Study_Count
1 500
2 69
3 44
4 21
5 27
6 17
7 9
8 9
9 11
10 12
11 13
12 7
13 8
14 5
15 9
16 5
17 3
18 6
19 2
20 4
22 11
23 3
24 5
25 6
26 1
27 2
28 6
29 1
30 2
31 1
32 3
33 7
34 3
35 5
36 2
37 1
38 3
39 2
42 3
43 3
44 1
46 2
50 3
51 2
52 2
56 1
58 2
59 1
60 1
61 1
63 1
64 1
66 1
69 1
70 1
71 1
75 2
76 1
78 1
79 1
81 2
83 1
84 1
86 1
87 1
88 1
91 2
94 1
97 1
101 3
102 1
103 1
105 1
107 1
108 1
115 1
117 2
119 2
122 1
123 2
128 1
130 1
134 1
139 1
153 1
157 1
170 1
171 1
173 2
176 1
186 1
187 1
188 1
198 1
199 1
211 1
212 1
215 1
222 1
224 1
225 1
239 1
244 1
299 1
551 1

Phase

Phase Study_Count
Phase 2 311
Phase 1 248
Phase 1/Phase 2 130
Phase 3 91
N/A 87
Phase 4 30
Phase 2/Phase 3 18
Early Phase 1 16

Number of Arms

Number_of_Arms Count_of_Studies
1 532
2 207
3 40
4 25
5 12
6 8
7 10
8 4
9 2
10 6
12 2
17 1
21 1
NA 81

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 6.000 2.0000 2.00000 1.00000 4.00000 10.0000 6.00 9.0000
1st Qu. 9.750 32.2500 18.00000 29.75000 33.00000 41.0000 162.50 71.2500
Median 19.000 57.0000 30.00000 42.00000 55.00000 80.0000 392.00 107.5000
Mean 24.375 225.6905 37.13469 65.53125 77.47869 182.6667 1056.89 298.7333
3rd Qu. 33.250 111.7500 48.00000 70.75000 97.00000 142.5000 841.00 365.0000
Max. 72.000 4000.0000 330.00000 942.00000 470.00000 1000.0000 9350.00 2600.0000

Trial Group Type

group_type Group_Count
Experimental 1214
Active Comparator 166
NA 81
Other 74
No Intervention 40
Placebo Comparator 21
Sham Comparator 1

Intervention Model

intervention_model Study_Count
Single Group Assignment 621
Parallel Assignment 237
NA 28
Sequential Assignment 27
Crossover Assignment 10
Factorial Assignment 8

Primary Purpose

primary_purpose Study_Count
Treatment 836
Supportive Care 51
Prevention 25
Basic Science 7
NA 5
Other 3
Diagnostic 2
Health Services Research 2

Observational Studies

Studies by Country

Country Study_Count
United States 46
NA 15
Denmark 8
France 5
Israel 5
Canada 2
China 2
Italy 2
Korea, Republic of 2
Mexico 2
Spain 2
United States|Australia|Canada 2
United States|Australia|Canada|New Zealand|Puerto Rico|Switzerland 2
Austria|Germany|Italy 1
Belgium 1
Belgium|France|Portugal 1
Brazil 1
Czech Republic|France|Germany|Italy|Poland|Russian Federation|Spain|United Kingdom 1
Denmark|Finland|Iceland|Lithuania|Norway|Sweden 1
Denmark|Finland|Iceland|Norway|Sweden 1
Denmark|France|Germany|Israel|Italy|Netherlands|Poland|Russian Federation|Spain 1
Egypt 1
Greece 1
Guatemala 1
India 1
Indonesia 1
Ireland|United Kingdom 1
Sweden 1
Turkey 1
United Kingdom 1
United States|Australia|Canada|Ireland|New Zealand|Puerto Rico|Switzerland 1
United States|Australia|Canada|New Zealand 1
United States|Australia|Canada|Puerto Rico 1
United States|Australia|Canada|Puerto Rico|Switzerland 1
United States|Belgium|Canada|Germany|Netherlands|United Kingdom 1
United States|Canada 1
United States|Czech Republic|France|Germany|Italy|Poland|Spain|United Kingdom 1
United States|Puerto Rico 1

Sites per Study

Site_count Study_Count
1 79
2 5
3 5
4 2
5 2
9 1
10 2
12 2
19 2
21 1
31 3
32 1
33 1
38 1
41 1
51 1
66 1
79 1
112 1
135 1
137 1
144 1
164 1
183 1
192 1
200 1
244 1

Enrollment Metrics

Measure Observational
Min 4.000
1st Qu 45.000
Median 150.000
Mean 1566.076
3rd Qu 408.500
Max 99999.000

Observation Model

observational_model Study_Count
Cohort 59
Case-Only 28
NA 11
Other 9
Case Control 6
Case-Control 4
Case-Crossover 1
Defined Population, Natural History 1
Family-Based 1

Time Perspective

time_perspective Study_Count
Prospective 60
Retrospective 41
Cross-Sectional 6
NA 6
Other 5
Cross-Sectional, Retrospective 1
Longitudinal, Prospective 1

Registries

Studies by Country

Country Study_Count
United States 3
China 1
Germany 1
Indonesia 1
Italy 1
Sweden 1

Sites per Study

Site_count Study_Count
1 5
2 1
7 1
51 1

Enrollment Metrics

Measure Registries
Min 24.000
1st Qu 124.000
Median 370.500
Mean 1750.125
3rd Qu 1250.000
Max 10000.000

Registry Model

observational_model Study_Count
Other 4
Cohort 3
Case-Only 1

Time Perspective

time_perspective Study_Count
Prospective 6
Cross-Sectional 1
Other 1

Follow-up

target_duration Study_Count
1 Year 3
1 Day 1
10 Years 1
15 Years 1
20 Years 1
5 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT04456959 InO - A Retrospective Study of UK Patients With Leukaemia https://ClinicalTrials.gov/show/NCT04456959 Recruiting Pfizer 2020-12-31
NCT03627208 Optimal Methods of Disease Detection in Children and Young Adults With Acute Lymphoblastic Leukemia in the Pediatric Oncology Branch https://ClinicalTrials.gov/show/NCT03627208 Enrolling by invitation National Institutes of Health Clinical Center (CC) 2021-12-31
NCT03279900 Hematotoxicity in Acute Lymphoblastic Leukemia Children in Maintenance Phase Therapy https://ClinicalTrials.gov/show/NCT03279900 Completed Indonesia University 2018-05-16
NCT03260101 Non-interventional, Long-term Follow-up of Subjects Who Completed ApoGraft-01 Study https://ClinicalTrials.gov/show/NCT03260101 Recruiting Cellect Biotechnology 2021-12-31
NCT03190499 Quality of Life in Children With Cancer https://ClinicalTrials.gov/show/NCT03190499 Completed Cumhuriyet University 2018-08-01
NCT03123887 Evaluate the Hematological Remission Rates and Survival Among Chinese Adult Patients With B-precursor ALL https://ClinicalTrials.gov/show/NCT03123887 Completed Harbin Hematology and Oncology Institute 2016-06-03
NCT03067584 Genetic Study of Familial Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT03067584 Completed St. Jude Children’s Research Hospital 2017-06-23
NCT03000335 Evaluation of ProALL miRs in Blood Specimen for Prediction of ALL Relapse Risk https://ClinicalTrials.gov/show/NCT03000335 Recruiting Curewize Health Ltd. 2020-05-31
NCT02888977 Tyrosine Kinase Inhibitors and Low Intensity Chemotherapy in Ph+ ALL https://ClinicalTrials.gov/show/NCT02888977 Recruiting Versailles Hospital 2020-12-31
NCT02813252 Long-Term Follow-up Study for Patients Previously Treated With JCAR015 https://ClinicalTrials.gov/show/NCT02813252 Active, not recruiting Juno Therapeutics, a Subsidiary of Celgene 2032-09-30
NCT02783651 An Study of Patients With Ph- Chromosome-negative Relapsed or Refractory Acute Lymphoblastic Leukemia in the US https://ClinicalTrials.gov/show/NCT02783651 Completed Amgen 2020-03-31
NCT02767388 Electrophysiological Biomarkers of Chemotherapy-related Cognitive Impairment and Recovery https://ClinicalTrials.gov/show/NCT02767388 Completed University of Nebraska 2017-12-11
NCT02759822 Haploidentical Hematopoietic Stem Cell Transplantation for Acute Leukemias https://ClinicalTrials.gov/show/NCT02759822 Recruiting Instituto Nacional de Cancer, Brazil 2021-04-30
NCT02617004 Multicenter Trial Treatment of Philadelphia Chromosome Negative B-cell Acute Lymphoblastic Leukemia of Young Adults https://ClinicalTrials.gov/show/NCT02617004 Recruiting Assistance Publique - Hôpitaux de Paris 2020-12-31
NCT00923442 Biology Studies of Hematologic Cancers https://ClinicalTrials.gov/show/NCT00923442 Enrolling by invitation National Institutes of Health Clinical Center (CC) NA
NCT01351545 A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) https://ClinicalTrials.gov/show/NCT01351545 Recruiting Center for International Blood and Marrow Transplant Research 2021-10-31
NCT00268528 Study to Assess Compliance With Long-Term Mercaptopurine Treatment in Young Patients With Acute Lymphoblastic Leukemia in Remission https://ClinicalTrials.gov/show/NCT00268528 Completed Children’s Oncology Group 2012-03-05
NCT00026780 Eligibility Screening for a NCI Pediatric Oncology Branch Research Study https://ClinicalTrials.gov/show/NCT00026780 Enrolling by invitation National Institutes of Health Clinical Center (CC) NA
NCT02338479 Natural History and Biology of Long-Term Late Effects Following Hematopoietic Cell Transplant for Childhood Hematologic Malignancies https://ClinicalTrials.gov/show/NCT02338479 Active, not recruiting Center for International Blood and Marrow Transplant Research 2020-02-29
NCT02303522 Historical Data Analysis of Complete Remission in Children With R/R Acute Lymphoblastic Leukemia (ALL) https://ClinicalTrials.gov/show/NCT02303522 Completed Amgen 2015-01-22
NCT02272673 The Effects of Honey on Febrile Neutropenia in Children With Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT02272673 Completed Ain Shams University 2013-08-31
NCT02256137 A Longitudinal Assessment of Frailty in Young Adult Survivors of Childhood Cancer https://ClinicalTrials.gov/show/NCT02256137 Recruiting St. Jude Children’s Research Hospital 2021-06-30
NCT02188290 Transplant-Related Mortality in Patients Undergoing a Peripheral Blood Stem Cell Transplantation or an Umbilical Cord Blood Transplantation https://ClinicalTrials.gov/show/NCT02188290 Completed Kiadis Pharma 2015-06-30
NCT01295476 Biomarker Study in Bone Marrow Samples From Patients With T-Cell Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT01295476 Completed Children’s Oncology Group 2013-05-31
NCT01284010 Biomarkers in Blood and Bone Marrow Samples From Patients With Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT01284010 Completed Alliance for Clinical Trials in Oncology 2014-09-30
NCT02010931 Retrospective Analysis of Survival in Adult MRD Positive Acute Lymphoblastic Leukemia Patients https://ClinicalTrials.gov/show/NCT02010931 Completed Amgen 2014-03-31
NCT02003612 Historical Data Analysis of Hematological Remission and Survival in Adults With R/R Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT02003612 Completed Amgen 2014-01-31
NCT01976442 Use of Saline-Washed Platelet and Red Cell Transfusions in Adult Acute Leukemia https://ClinicalTrials.gov/show/NCT01976442 Completed University of Rochester 2016-11-30
NCT01965171 Transfusional Iron Overload Among Leukemia Survivors https://ClinicalTrials.gov/show/NCT01965171 Completed St. Jude Children’s Research Hospital 2017-05-31
NCT01896752 Renal and Hepatic Clearance Following High-Dose Methotrexate in Childhood ALL https://ClinicalTrials.gov/show/NCT01896752 Completed Rigshospitalet, Denmark 2013-01-31
NCT01886651 The Influence of Thiopurine Methyltransferase Activity on Toxicity After High-dose Methotrexate in Childhood Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT01886651 Completed Rigshospitalet, Denmark 2012-02-29
NCT01790152 Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment https://ClinicalTrials.gov/show/NCT01790152 Recruiting Children’s Oncology Group 2022-03-30
NCT01678508 Pharmacogenetically Based Dosing of Thiopurines in Childhood Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT01678508 Completed Rigshospitalet, Denmark 2011-07-31
NCT01663129 Steroid-Induced Osteoporosis in the Pediatric Population - Canadian Incidence Study https://ClinicalTrials.gov/show/NCT01663129 Completed Children’s Hospital of Eastern Ontario 2014-03-06
NCT01626183 Studying RNA in Samples From Younger Patients With T-Cell Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT01626183 Completed Children’s Oncology Group 2016-05-31
NCT01623856 Studying Genes Associated With Non-Hodgkin Lymphoma in Young Patients https://ClinicalTrials.gov/show/NCT01623856 Completed Children’s Oncology Group 2012-06-30
NCT01625143 Studying Genes in Samples From Younger Patients With Relapsed Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT01625143 Completed Children’s Oncology Group 2016-05-31
NCT01581528 Studying Samples From Patients With T-Cell Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT01581528 Completed Children’s Oncology Group 2016-05-31
NCT01565447 Acute Lymphoblastic Leukemia (ALL) and Lymphoblastic Lymphoma Gait Parameters Study https://ClinicalTrials.gov/show/NCT01565447 Active, not recruiting Oregon Health and Science University 2020-12-31
NCT01556386 Pharmacogenetic Analysis of Korean Pediatric Patients With Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT01556386 Completed Seoul National University Hospital 2012-03-31
NCT01553162 Studying Dexamethasone and Prednisone Sensitivity in Samples From Younger Patients With High-Risk B-Cell Precursor Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT01553162 Completed Children’s Oncology Group 2016-05-31
NCT01533168 Genetic Test To Identify Previously Undetectable Minimal Residual Disease in Cell Samples From Younger Patients With Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT01533168 Completed Children’s Oncology Group 2016-05-31
NCT01540812 Treatment of Acute Lymphoblastic Leukemia HIGH RISK BCR / ABL NEGATIVE IN ADULTS https://ClinicalTrials.gov/show/NCT01540812 Completed PETHEMA Foundation 2019-11-20
NCT01540578 Studying Biomarkers as a Diagnostic Tool in Samples From Younger Patients With B-Cell Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT01540578 Completed Children’s Oncology Group 2016-05-31
NCT01520246 Gene Expression in Samples From Patients With T-Cell Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT01520246 Completed Children’s Oncology Group 2016-07-31
NCT01505699 Biomarkers in Samples From Patients With B-Cell Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT01505699 Completed Eastern Cooperative Oncology Group 2012-02-06
NCT01476462 Second Malignant Neoplasms After Childhood ALL Therapy https://ClinicalTrials.gov/show/NCT01476462 Completed Rigshospitalet, Denmark 2011-04-30
NCT01470924 Acute Lymphoblastic Leukemia Relapse in Sweden 2003-2007 https://ClinicalTrials.gov/show/NCT01470924 Completed Region Örebro County NA
NCT01439217 Endothelial Function, Arterial Stiffness and Components https://ClinicalTrials.gov/show/NCT01439217 Completed Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 2013-02-28
NCT01393249 PEG-Asparaginase Associated Pancreatitis, Hepatotoxicity and Hyperlipidemia in Children With ALL https://ClinicalTrials.gov/show/NCT01393249 Completed Rigshospitalet, Denmark 2013-12-31
NCT01380587 Utility of XCL1 as a Prognostic Marker in Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT01380587 Completed Hospital Universitario Dr. Jose E. Gonzalez 2012-09-30
NCT04364451 Correlation of Polymorphisms of Lipoprotein Lipase (LpL) and Apolipoprotein E (Apo E) With Lipid Profile of Children With Acute Lymphoblastic Eukaemia During Therapy With L - Asparaginase. https://ClinicalTrials.gov/show/NCT04364451 Recruiting Aristotle University Of Thessaloniki 2022-08-31
NCT04322084 Continuous Ambulatory Monitoring to Predict Elevated Risk of Infection in Children With Lymphoblastic Leukemia Undergoing Induction Chemotherapy (CAMPER-ALL) https://ClinicalTrials.gov/show/NCT04322084 Recruiting St. Jude Children’s Research Hospital 2021-05-01
NCT04320992 A Multicenter Prospective Study of “High Risk” Molecular Typing in Patients With Adult T Lymphoblastic Lymphoma https://ClinicalTrials.gov/show/NCT04320992 Recruiting Sun Yat-sen University 2023-03-31
NCT04290000 Collection of Biological Samples From Patients Treated With CAR-T Cells for Hematological Malignancies https://ClinicalTrials.gov/show/NCT04290000 Recruiting University Hospital, Montpellier 2025-02-25
NCT04271215 Overweight and Obesity as Prognostic Factors for Survival in Children With Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT04271215 Recruiting Coordinación de Investigación en Salud, Mexico 2020-12-31
NCT04187248 The Association Between Asparaginase Enzyme Activity Levels and Toxicities in Childhood Acute Lymphoblastic Leukaemia in NOPHOALL 2008 https://ClinicalTrials.gov/show/NCT04187248 Completed Aarhus University Hospital 2016-02-28
NCT04158011 A Retrospective Study of Patients With Leukemia Relapse in the CNS Treated With CAR T Cells https://ClinicalTrials.gov/show/NCT04158011 Active, not recruiting Sheba Medical Center 2020-03-01
NCT04055558 Lymphoproliferative Disorders During the Treatment of Childhood Acute Lymphoblastic Leukemia/Lymphoma https://ClinicalTrials.gov/show/NCT04055558 Recruiting Rabin Medical Center 2019-12-18
NCT03985826 Primary Health Care Utilisation Among Survivors of Childhood Acute Lymphoblastic Leukaemia https://ClinicalTrials.gov/show/NCT03985826 Completed University of Aarhus 2019-11-30
NCT03974893 Dietary Intake, Sarcopenic Obesity, and Other Treatment-Related Outcomes in Indian Children With Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT03974893 Recruiting Columbia University 2021-11-30
NCT03911128 A Treatment Protocol for Participants 1-45 Years With Acute Lymphoblastic Leukaemia https://ClinicalTrials.gov/show/NCT03911128 Recruiting Karolinska University Hospital 2020-03-31
NCT03898128 ItaliaN Observational Study of Patients With Acute Lymphoblastic Leukemia Treated With Anti-CD22 Immunoconjugate https://ClinicalTrials.gov/show/NCT03898128 Recruiting Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori 2020-10-31
NCT03860376 Ex Vivo Drug Sensitivity Testing and Mutation Profiling https://ClinicalTrials.gov/show/NCT03860376 Recruiting Florida International University 2022-12-15
NCT03803670 Clinical Significance of Occult Central Nervous System Disease In Adult Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT03803670 Completed University of Rome Tor Vergata 2019-01-01
NCT03751072 Efficacy and Toxicity of Blinatumomab in the French ATU for Adult BCP-ALL R/R, or With MRD+ (FRENCH-CYTO) https://ClinicalTrials.gov/show/NCT03751072 Recruiting Group for Research in Adult Acute Lymphoblastic Leukemia 2018-11-30
NCT03709017 Iclusig PMS in CML or Ph+ALL Patients https://ClinicalTrials.gov/show/NCT03709017 Recruiting Korea Otsuka Pharmaceutical Co., Ltd. 2023-06-30
NCT03678454 Iclusig® (Ponatinib) in Clinical Practice for the Treatment of Chronic Myeloid Leukemia or Ph+ Acute Lymphoblastic Leukemia in Belgium https://ClinicalTrials.gov/show/NCT03678454 Recruiting Incyte Corporation 2022-03-31
NCT03581045 Postural Control Under Different Cognitive Loads in Adult Survivors of Acute Lymphoblastic Leukemia and Age-Matched Healthy Individuals https://ClinicalTrials.gov/show/NCT03581045 Active, not recruiting St. Jude Children’s Research Hospital 2020-06-30
NCT03568266 Pharmacogenomics of Asparaginase Induced Hepatotoxicity https://ClinicalTrials.gov/show/NCT03568266 Recruiting University of Southern California 2024-05-22
NCT03571997 Study of Prognostic Factors in Adult Lymphoblastic Lymphoma https://ClinicalTrials.gov/show/NCT03571997 Recruiting PETHEMA Foundation 2020-09-01
NCT03545659 Childhood Acute Lymphoblastic Leukaemia: Follow-Up https://ClinicalTrials.gov/show/NCT03545659 Recruiting University of Aarhus 2020-06-30
NCT03471416 Nutritional Status in Children With ALL in Guatemala https://ClinicalTrials.gov/show/NCT03471416 Recruiting Columbia University 2021-01-31
NCT03422731 Multi-modality Imaging and Collection of Biospecimen Samples in Understanding Bone Marrow Changes in Patients With Acute Myeloid Leukemia Undergoing TBI and Chemotherapy https://ClinicalTrials.gov/show/NCT03422731 Recruiting City of Hope Medical Center 2023-02-06
NCT01199562 Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant https://ClinicalTrials.gov/show/NCT01199562 Completed City of Hope Medical Center 2013-12-31
NCT01185886 Study of Blood and Tissue Samples in Children With Newly Diagnosed Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT01185886 Active, not recruiting European Organisation for Research and Treatment of Cancer - EORTC 2021-06-30
NCT01177527 Questionnaire and Tissue Banking For Multiple Myeloma, Waldenstrom Macroglobulinemia and Related Disorders https://ClinicalTrials.gov/show/NCT01177527 Active, not recruiting Dana-Farber Cancer Institute 2021-01-31
NCT01150669 Lestaurtinib With or Without Chemotherapy Agents in Samples From Young Patients With Leukemia https://ClinicalTrials.gov/show/NCT01150669 Completed Children’s Oncology Group 2016-05-31
NCT01148927 Quality of Life Study for Adult Patients With Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT01148927 Completed University Health Network, Toronto 2012-06-30
NCT01142427 Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT01142427 Active, not recruiting Children’s Oncology Group 2015-05-01
NCT01119586 Biomarkers in DNA Samples From Patients With High-Risk Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT01119586 Completed Children’s Oncology Group 2015-12-31
NCT01094392 Hemostasis During Asparaginase Treatment in Acute Lymphoblastic Leukemia(ALL) https://ClinicalTrials.gov/show/NCT01094392 Recruiting Aarhus University Hospital 2019-12-31
NCT01078337 T-cell Minimal Residual Disease (MRD) Evaluation Using Flow Cytometric Analysis https://ClinicalTrials.gov/show/NCT01078337 Completed Stanford University 2007-10-31
NCT01047020 Motor Proficiency And Physical Activity in Adult Survivors of Childhood Acute Lymphoblastic Leukemia (ALL) https://ClinicalTrials.gov/show/NCT01047020 Completed St. Jude Children’s Research Hospital 2013-04-30
NCT01016379 Studying DNA in Blood and Bone Marrow Samples From Young Patients With Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT01016379 Completed Children’s Oncology Group 2016-05-31
NCT01014195 Risk of Psychopathology and Neurocognitive Impairment in Leukemia Survivors https://ClinicalTrials.gov/show/NCT01014195 Completed St. Jude Children’s Research Hospital 2014-10-31
NCT01005277 Study of Biomarkers in DNA Samples From Patients With Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia https://ClinicalTrials.gov/show/NCT01005277 Active, not recruiting Children’s Oncology Group 2100-01-31
NCT00993135 Kidney Dysfunction in Children and Young Adults Who Have Received Methotrexate for Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT00993135 Completed Vanderbilt University Medical Center 2009-12-31
NCT00954720 Observational Study of Iron Overload in Stem Cell Transplantation https://ClinicalTrials.gov/show/NCT00954720 Completed Dana-Farber Cancer Institute 2011-01-31
NCT00949741 Observational Study for the Cytofluorimetric Analysis of Cerebrospinal Fluid in Non-Hodgkin’s Lymphoma Patients https://ClinicalTrials.gov/show/NCT00949741 Completed Gruppo Italiano Multiregionale per lo studio dei Linfomi e delle Leucemie 2011-10-31
NCT00899899 Resistance to Methotrexate in Patients With Acute Lymphoblastic Leukemia in Relapse or Remission https://ClinicalTrials.gov/show/NCT00899899 Completed Children’s Oncology Group 2005-03-31
NCT00899652 DNA Analysis of Bone Marrow and Blood Samples From Young Patients With Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT00899652 Completed Children’s Oncology Group 2005-09-30
NCT00899366 DNA Analysis of Tissue From Patients With T-Cell Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT00899366 Completed Eastern Cooperative Oncology Group 2009-07-30
NCT00898755 Collecting and Storing Tissue From Young Patients With Cancer https://ClinicalTrials.gov/show/NCT00898755 Completed Children’s Oncology Group 2008-07-17
NCT00898079 Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer https://ClinicalTrials.gov/show/NCT00898079 Completed Children’s Oncology Group 2018-06-30
NCT00898404 Response or Resistance to Chemotherapy in Young Patients With Acute Lymphoblastic Leukemia Treated With Methotrexate https://ClinicalTrials.gov/show/NCT00898404 Completed Children’s Oncology Group 2016-05-31
NCT00896766 Laboratory Study of Lymphoblasts in Young Patients With High-Risk Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT00896766 Completed Children’s Oncology Group 2016-05-31
NCT00897507 DNA Analysis of Tumor Tissue Samples From Young Patients With Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT00897507 Active, not recruiting Children’s Oncology Group 2100-01-31
NCT00897325 Collecting and Storing Samples of Bone Marrow and Blood From Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma https://ClinicalTrials.gov/show/NCT00897325 Completed Children’s Oncology Group 2019-12-31
NCT00866671 Observational Study of Nelarabine in Children and Young Adults https://ClinicalTrials.gov/show/NCT00866671 Completed GlaxoSmithKline 2014-09-30
NCT03647215 CALLS: CML and Ph+ALL Low Level Mutation Prevalence Survey https://ClinicalTrials.gov/show/NCT03647215 Recruiting Incyte Corporation 2020-06-30
NCT03642626 MT2017-45: CAR-T Cell Therapy for Heme Malignancies https://ClinicalTrials.gov/show/NCT03642626 Recruiting Masonic Cancer Center, University of Minnesota 2028-07-31
NCT03226704 Leukapheresis for CAR-Therapy Manufacturing https://ClinicalTrials.gov/show/NCT03226704 Recruiting National Institutes of Health Clinical Center (CC) 2023-05-01
NCT00801346 Metabolic Syndrome in Young Patients With Acute Lymphoblastic Leukemia in Remission https://ClinicalTrials.gov/show/NCT00801346 Completed Vanderbilt University Medical Center 2016-04-30
NCT04437420 Preclinical Project on the Traitment of Acute Lymphoblastique Leukemia With NVP-BEP800, an Inhibitor of the Heat Shock Protein HSP90 https://ClinicalTrials.gov/show/NCT04437420 Recruiting Centre Hospitalier Universitaire Dijon 2021-09-30
NCT00736749 Long-Term Follow-Up of Patients Who Have Participated in Children’s Oncology Group Studies https://ClinicalTrials.gov/show/NCT00736749 Recruiting Children’s Oncology Group 2100-01-31
NCT00719147 AVN of Weight-Bearing Joints In Patients With Hematologic Malignancies Treated With Dexamethasone Or Prednisone https://ClinicalTrials.gov/show/NCT00719147 Completed St. Jude Children’s Research Hospital 2005-07-31
NCT00674193 Evaluating Dactinomycin and Vincristine in Young Patients With Cancer https://ClinicalTrials.gov/show/NCT00674193 Completed Children’s Oncology Group 2016-06-30
NCT00664131 Neurologic Morbidity and Disability in Acute Lymphoblastic Leukemia Survivors https://ClinicalTrials.gov/show/NCT00664131 Completed St. Jude Children’s Research Hospital 2008-10-31
NCT00606216 Structural Imaging and Cognitive Functions in Adult Stem Cell Transplant Recipients Treated With Chemotherapy Alone or in Combination With Radiotherapy https://ClinicalTrials.gov/show/NCT00606216 Completed Memorial Sloan Kettering Cancer Center 2015-12-31
NCT00552825 Pulmonary Function at Presentation and Follow-up in Hemato-Oncology 3-7 Years Old Children https://ClinicalTrials.gov/show/NCT00552825 Completed Sheba Medical Center NA
NCT00505141 Urban Environmental Exposures and Childhood Cancer https://ClinicalTrials.gov/show/NCT00505141 Completed Georgetown University NA
NCT00513175 Non-Myeloablative Allogeneic Stem Cell Transplantation With Matched Unrelated Donors for Treatment of Hematologic Malignancies, Renal Cell Carcinoma, and Aplastic Anemia https://ClinicalTrials.gov/show/NCT00513175 Completed University of California, San Francisco NA
NCT00482352 Risk-Group Classification of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT00482352 Completed Children’s Oncology Group 2012-04-30
NCT00437060 Brain Function in Young Patients Receiving Methotrexate for Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT00437060 Completed Children’s Oncology Group 2015-09-30
NCT00330538 Osteoporosis in Children With ALL https://ClinicalTrials.gov/show/NCT00330538 Completed Children’s Mercy Hospital Kansas City NA
NCT00085176 Neurobehavioral Complications in Children Who Were Previously Treated With Steroids and Intrathecal Therapy for Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT00085176 Completed Children’s Oncology Group 2009-09-30
NCT00048958 Cytogenetic Studies in Acute Leukemia and Multiple Myeloma https://ClinicalTrials.gov/show/NCT00048958 Active, not recruiting Alliance for Clinical Trials in Oncology 2100-01-31
NCT00003861 Diagnostic Study of Patients With Acute Lymphoblastic Leukemia or Acute Promyelocytic Leukemia https://ClinicalTrials.gov/show/NCT00003861 Active, not recruiting Alliance for Clinical Trials in Oncology 2100-01-31
NCT00015587 Molecular Epidemiology of Childhood Leukemia (Aka The California Childhood Leukemia Study) https://ClinicalTrials.gov/show/NCT00015587 Completed National Institute of Environmental Health Sciences (NIEHS) 2016-07-31

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03821727 SCT in Ph Positive Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT03821727 Completed University Hospital, Udine, Italy 2017-12-31
NCT03255668 Hematotoxicity in Maintenance Therapy of Children With Acute Lymphoblastic Leukemia https://ClinicalTrials.gov/show/NCT03255668 Completed Indonesia University 2018-10-15
NCT02872987 GMALL Registry and Collection of Biomaterial: Prospective Data Collection Regarding Diagnosis, Treatment and Outcome of Adult Acute Lymphoblastic Leukemia (ALL) Patients and Related Diseases Associated With a Prospective Collection of Biomaterial https://ClinicalTrials.gov/show/NCT02872987 Recruiting Goethe University 2025-12-31
NCT01950286 Hyper-CVAD Treatment of Adult T-cell Acute Lymphoblastic Leukemia in Sweden. https://ClinicalTrials.gov/show/NCT01950286 Completed Region Örebro County 2013-02-28
NCT01890486 The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen https://ClinicalTrials.gov/show/NCT01890486 Recruiting Wake Forest University Health Sciences 2023-05-31
NCT04014764 Collect and Assess Tissue Samples From Subjects With Hematologic Malignancy https://ClinicalTrials.gov/show/NCT04014764 Recruiting Notable Labs 2022-09-30
NCT03971318 A Prospective Multicenters Clinical Cohort Study of Stratified Treatment of Chinese Children With LBL https://ClinicalTrials.gov/show/NCT03971318 Recruiting Sun Yat-sen University 2022-05-05
NCT03760237 Cardiovascular Function in Acute Leukemia https://ClinicalTrials.gov/show/NCT03760237 Enrolling by invitation Abramson Cancer Center of the University of Pennsylvania 2021-12-31